Cervical Cytology Report

Analysis Summary:
Cervical cytology reveals a cluster of squamous cells exhibiting significant atypia, consistent with a high-grade squamous intraepithelial lesion (HSIL). The model predicts a high-grade lesion with 98.52% probability. Qualitative analysis shows marked nuclear enlargement (average nuclear diameter exceeding 10µm in 75% of cells), hyperchromasia, and significant nuclear pleomorphism (variation in nuclear shape and size). Cytoplasmic features include an increased nuclear-to-cytoplasmic ratio, exceeding 0.7 in at least 90% of the cells and demonstrating marked irregularity of cytoplasmic borders in at least 50% of the cells. Architectural findings from the whole-field image show a complete loss of normal cell polarity and organization of the cell cluster, supporting the diagnosis of HSIL. Immediate colposcopy with directed biopsy is recommended to confirm the diagnosis, assess the extent of the lesion, and exclude the presence of invasive carcinoma.